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January 22, 2017

Investigators dug back into the Adenoma Prevention With Celecoxib (APC) tissue archives to identify biomarkers that distinguish those individuals at high risk for colorectal adenomas who stand to derive greatest benefit from celecoxib chemoprevention.

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January 21, 2017

Findings from a prospective phase II trial suggest that treatment with cabozantinib monotherapy confers marked clinical benefit in patients with progressive, well-differentiated neuroendocrine tumors—lesions that historically are difficult to treat given their chemoresistant nature.

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January 21, 2017

Inhibiting both BRAF and EGFR within the MAPK pathway proves promising for staunching tumor growth in select cases of metastatic colorectal cancer based on interim results of the phase II SWOG S1406 trial.

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January 21, 2017

Preliminary data from the phase I/II CheckMate 040 study of nivolumab suggest that the anti-PD-1 antibody is both active and well tolerated when given as first- or second-line monotherapy to patients with advanced HCC.

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January 21, 2017

Results of this small feasibility study suggest that stereotactic body radiation therapy may be an alternative bridging option for patients with locally advanced disease—one that can be performed in the outpatient setting while potentially causing minimal major morbidity.

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January 21, 2017

Level I evidence supporting the benefit of adjuvant therapy in localized biliary cancer remains elusive based on the negative results of the PRODIGE 12–ACCORD 18 trial that compared GEMOX versus surveillance.

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January 20, 2017

Nivolumab represents the first immunotherapy in phase III analyses to significantly improve OS, PFS, and ORR in patients with advanced gastric or gastroesophageal junction cancer, fulfilling a dire need for effective salvage therapy for a subgroup of patients.

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January 19, 2017

This phase II trial demonstrates that using PET imaging following initial induction chemotherapy to assess early response can maximize pCR rates in esophageal adenocarcinoma by signaling the need to switch from ineffective to alternative chemotherapy during preoperative chemoradiation.

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January 12, 2017

Dr. Florian Lordick outlines the evolving classification of gastric cancer and discusses recent studies on emerging treatment options. 

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January 12, 2017

Drs. Young and Chau review several early-phase studies on combination immunotherapy treatments for GI cancers and what these studies have uncovered about the certain tumor types that are responsive and those that are poorly immunogenic. 

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January 12, 2017

Drs. Manisha Palta, Christopher Willett, and Brian Czito discuss the current data on stereotactic body radiotherapy for the treatment of HCC and future research directions.

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January 12, 2017

Experts discuss the initial data from the RESORCE trial, which explored the second-line use of regorafenib in patients with advanced hepatocellular carcinoma.

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January 12, 2017

How does the location of colon cancer tumors impact clinical decisions?

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January 12, 2017

Dr. Philip highlights several recent and ongoing studies in the field of pancreatic cancer and identifies the biggest hurdles that research must overcome.

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January 12, 2017

Dr. Jorge Gallardo and colleagues discuss the epidemiology of esophageal, gastric, liver, gallbladder, pancreatic, colon, and rectal cancers in Chile and how the country’s changing demographics across the past 20 years have increased cancer mortality rates.

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January 12, 2017

Drs. Mariela Blum Murphy and Jaffer A. Ajani discuss the latest research on immune checkpoint inhibitors for advanced gastroesophageal cancers.

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January 12, 2017

Listen to the latest ASCO Daily News podcast.

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January 12, 2017

Early-career attendees of the GI Symposium can join renowned faculty for an informal networking luncheon to discuss career development topics.

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January 12, 2017

ASCO’s Quality Training Program will now be held at regional locations. 

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January 12, 2017

ASCO has launched JCO Clinical Cancer Informatics, which will be dedicated to applications of biomedical informatics to cancer care.

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